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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRP9
All Species:
22.42
Human Site:
S458
Identified Species:
41.11
UniProt:
O43818
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43818
NP_004695.1
475
51841
S458
R
I
K
E
A
R
N
S
V
C
I
I
P
L
R
Chimpanzee
Pan troglodytes
XP_001170125
475
51836
S458
R
I
K
E
A
R
N
S
V
C
I
I
P
L
R
Rhesus Macaque
Macaca mulatta
XP_001087877
541
58617
S524
R
I
K
E
A
R
N
S
V
C
I
I
P
L
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WM3
475
52089
S458
R
I
K
E
A
R
N
S
V
C
I
I
P
L
R
Rat
Rattus norvegicus
NP_001102248
478
52484
S461
R
I
K
E
A
R
N
S
V
C
I
I
P
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414243
454
49618
C435
T
L
Y
M
N
S
I
C
I
I
P
L
K
C
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P5M2
305
33318
S291
P
T
G
S
K
I
V
S
A
G
D
D
R
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001014529
484
53267
Q470
R
L
K
E
A
K
N
Q
V
V
V
L
D
V
K
Honey Bee
Apis mellifera
XP_394355
328
36323
K314
W
W
R
I
P
E
A
K
N
V
I
V
I
I
P
Nematode Worm
Caenorhab. elegans
NP_872030
518
56758
Q453
V
D
R
E
A
R
N
Q
V
V
I
L
P
I
K
Sea Urchin
Strong. purpuratus
XP_787944
475
52623
S460
R
L
K
E
A
K
N
S
I
V
I
V
R
L
R
Poplar Tree
Populus trichocarpa
XP_002306239
502
55779
N487
R
L
G
R
W
G
H
N
S
A
A
R
N
G
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06506
573
65036
R538
K
H
G
K
E
K
F
R
I
L
A
S
I
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.8
N.A.
N.A.
92.6
92.6
N.A.
N.A.
60
N.A.
22.1
N.A.
42.5
35.7
33.4
50.9
Protein Similarity:
100
100
87.4
N.A.
N.A.
94.9
94.5
N.A.
N.A.
73.8
N.A.
35.1
N.A.
61.3
48.2
52.5
68
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
6.6
N.A.
6.6
N.A.
40
6.6
46.6
60
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
26.6
N.A.
6.6
N.A.
80
26.6
73.3
86.6
Percent
Protein Identity:
37.4
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
57.5
N.A.
N.A.
N.A.
45.7
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
62
0
8
0
8
8
16
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
39
0
0
0
8
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
8
8
0
0
% D
% Glu:
0
0
0
62
8
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
24
0
0
8
0
0
0
8
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
39
0
8
0
8
8
0
24
8
62
39
16
16
8
% I
% Lys:
8
0
54
8
8
24
0
8
0
0
0
0
8
0
24
% K
% Leu:
0
31
0
0
0
0
0
0
0
8
0
24
0
47
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
62
8
8
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
0
0
8
0
47
0
8
% P
% Gln:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% Q
% Arg:
62
0
16
8
0
47
0
8
0
0
0
8
16
0
54
% R
% Ser:
0
0
0
8
0
8
0
54
8
0
0
8
0
0
0
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
0
54
31
8
16
0
8
8
% V
% Trp:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _